In 1956, Atlas Comics (precursor to Marvel) began publishing Dan DeCarlo's short-lived humor series Sherry the Showgirl. In 1964, Stan Lee and Steve Ditko introduced the villainous Kraven the Hunter in the pages of The Amazing Spider-Man. In a storyline beginning in 2012, Stan Lee, his brother Larry Lieber, and Alex Saviuk paired the two up in the Spider-Man newspaper strip.
Stan Lee has the weirdest ships you guys seriously
(Cover scans courtesy of comics.org, newspaper strip courtesy Comics Curmudgeon.)
